OPEN Repository

Welcome to OPEN - the Repository of Open Scientific Publications, run by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw, previously operating as the CeON Repository. The Repository enables Polish researchers from all fields to openly share their articles, books, conference materials, reports, doctoral theses, and other scientific texts.

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22798 archived items

Recent Submissions

Diabulimia – a diagnostic and therapeutic challenge in the Emergency Department
(Medical University of Gdańsk, 2024-06-28) Atriham, Adan R.; Kleszczyński, Jacek; Sierakowska, Alicja; Springer, Janusz; Emergency Department, River Oaks Hospital, Houston, USA; Emergency Department, University of Opole, Poland; Emergency Medicine and Medical Simulation Student Scientific Club, University of Opole, Poland; Division of Preventive Medicine & Education, Medical University of Gdańsk, Poland
Diabulimia is the intentional omission or reduction of insulin administration in a patient with insulin-dependent diabetes mellitus (IDDM) and a coexisting eating disorder in the attempt to reduce or avoid weight gain. Although the true incidence of diabulimia is unknown, it is estimated that between 20-30% of girls and up to 40% young women with IDDM have experienced diabulimia since their diagnosis of IDDM was made. Patients with diabulimia frequently present to the emergency department, therefore early recognition of the eating disorder and prompt psychiatric consultation are essential. The aim of this review article is to summarize the existing literature about diabulimia and to raise awareness amongst emergency physicians about how to identify and treat these patients.
Post-development sentiment and statistical analysis of different groups of psychiatric medications
(Medical University of Gdańsk, 2024-06-28) Toosi, Farshad Ghassemi; Toussi, Alireza Ghassemi; Department of Computer Science, Munster Technological University, Cork, Ireland; Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Background: medications are complex and influence the body in multiple ways. Post-development analysis of medications remains highly advantageous, as it allows for comprehensive understanding of the safety profile over extended periods and can direct future improvements to enhance the therapeutic benefits while minimizing risks. Our primary goal was to examine whether a substantial relationship exists between such patient experiences and the statistical analysis of data about the same medications from clinical trials. Methods: Patient feedback regarding medication commonly prescribed for psychiatric conditions was obtained from a publicly available website We searched for statistical analysis regarding the same medications. Data from was subjected to sentiment analysis, while data underwent statistical analysis. Results: the findings suggest a general connection between the two data sources. Medications with a greater amount of patient feedback generally attract more research attention, although with some exceptions. Additionally, medications approved for children receive less feedback online compared to those for adults and seniors. Medications for seniors receive more positive and neutral feedback in contrast to those for children and adults. Conclusions: online platforms offer a space for patients to share their experiences with using specific medications, potentially contributing to the enhancement of patient care and aiding researchers in further studies.
Edmonton Frail Scale – caregiver is a reliable source of information about the functional status of a hospitalized elderly patient
(Medical University of Gdańsk, 2024-06-28) Stolc, Bogna; Kleczewska, Agata; Kulak, Maria; Mierzejewska, Monika; Łyczek, Weronika; Zęgota, Tomasz; Wierzba, Karol; Department of Adult Psychiatry, University Clinical Centre in Gdańsk, Poland; Department of Nephrology, Dialysis and Internal Medicine, University Clinical Centre of the Medical University of Warsaw, Poland; Pomeranian Hospitals LLC, Polish Red Cross Maritime Hospital, Gdynia, Poland; Division of Nuclear Medicine, Medical University of Gdańsk, Poland; Non-public Health Care Centre “Przychodnia Aksamitna”, Gdańsk, Poland; Advanced Analysis - Big Data, SGH Warsaw School of Economics, Poland; Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdańsk, Poland
Background: The success of geriatric care requires cooperation with the patient’s caregivers. This study aims to compare the perspectives of elderly patients and their caregivers on functional efficiency, as measured by the Edmonton Frail Scale. By examining the discrepancies in these assessments, we hope to better understand perceptions of frailty-related functional limitations and improve the personalized approaches in geriatric care. Material and methods: This cross-sectional study enrolled a sample of hospitalized patients, based on availability of researchers. Exclusion criteria involved: age < 65, communication barriers, manual disability, exacerbation of a chronic disease or acute condition, no contact to the caregiver, lack of consent. The McNemar-Bowker test and the Wilcoxon signed-rank test were used to compare patients’ and their caregivers’ responses. Results: Forty five patients were enrolled. The answers concerning cognitive functions, laundry, and functional performance were statistically different (p < 0.001). Whereas after applying the Holm-Bonferroni method for multiple testing only the judgment of cognitive functions remained statistically different. Other domains showed no statistical differences. Conclusions: Our results may in general confirm the credibility of caregivers’ perspective in the patients’ functional assessment.
Association of hand grip strength with psychological stress, exercise habits and body composition amongst medical students: a cross-sectional study
(Medical University of Gdańsk, 2024-06-28) Barre, Samira; Inyingi, Laura; Orrego Castellanos, Julianna; Patel, Agastya; Ruckemann-Dziurdzinska, Katarzyna Anna; Bryl, Ewa Dorota; Witkowski, Jacek Maciej; Department of Pathophysiology, Medical University of Gdańsk, Poland; Department of Embryology, Medical University of Gdańsk, Poland
Background: The aim of this study was to assess the effectiveness of hand grip strength (HGS) test in identifying highly stressed individuals and to examine the effect of exercise and lifestyle on HGS and stress measures. Material and method: It is cross-sectional study. Students of the Medical University of Gdańsk, Poland were asked to fill out a questionnaire, undergo body composition analysis, perform HGS test and provide a saliva sample for cortisol measurement. Results: Self-rated stress (SRS) was significantly higher in pre-clinical years (PCY) compared to clinical years (CY). HGS was significantly lower in PCY males than CY males. Participants who performed some form of exercise had significantly higher HGS compared with those who did not exercise. A positive correlation between HGS and BMI was noted. Students with low HGS were found to have lower levels of salivary cortisol (SC). However, there was no significant difference in SC levels between PCY and CY students. Conclusions: HGS may be a reliable method of identifying stressed individuals and promoting healthy lifestyle behaviors. HGS testing is a safe, cheap and easy to perform method for a large number of participants while being time economical.
Precision medicine and improving the outcomes of atrial tachycardia ablation: a comprehensive review
(Medical University of Gdańsk, 2024-06-28) Młyński, Mikołaj; Sławiński, Grzegorz; Kozłowski, Dariusz; Department of Cardiology and Electrotherapy, Medical University of Gdańsk, Poland; Institute of Health Sciences, Pomeranian University in Słupsk, Słupsk, Poland
Atrial tachycardia (AT) is a prevalent cardiac arrhythmia characterized by rapid, abnormal electrical activity originating from the atria. It represents a significant clinical challenge due to its potential for recurrence, adverse cardiovascular outcomes and impact on quality of life. Catheter ablation has emerged as a primary therapeutic modality for AT, offering the potential for rhythm control and symptom alleviation. Despite advancements in techniques and technology, the success of AT ablation can vary widely among patients. Identifying prognostic factors associated with successful AT ablation and potential outcome improving techniques is imperative for optimizing patient care.