Microfluidics for antibiotic susceptibility testing

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dc.contributor.authorPostek, Witold
dc.contributor.authorPacocha, Natalia
dc.contributor.authorGarstecki, Piotr
dc.contributor.organizationInstitute of Physical Chemistry, Polish Academy of Sciencesen
dc.contributor.organizationBroad Institute of MIT and Harvard, Cambridge, USAen
dc.date.accessioned2022-09-22T12:38:36Z
dc.date.available2022-09-22T12:38:36Z
dc.date.issued2022-09
dc.description.abstractThe rise of antibiotic resistance is a threat to global health. Rapid and comprehensive analysis of infectious strains is critical to reducing the global use of antibiotics, as informed antibiotic use could slow down the emergence of resistant strains worldwide. Multiple platforms for antibiotic susceptibility testing (AST) have been developed with the use of microfluidic solutions. Here we describe microfluidic systems that have been proposed to aid AST. We identify the key contributions in overcoming outstanding challenges associated with the required degree of multiplexing, reduction of detection time, scalability, ease of use, and capacity for commercialization. We introduce the reader to microfluidics in general, and we analyze the challenges and opportunities related to the field of microfluidic AST.en
dc.description.sponsorshipNarodowe Centrum Nauki (NCN), Polish National Agency for Academic Exchange (NAWA), Foundation for Polish Science (FNP)
dc.identifier.citationLab Chip, 2022, 10.1039/d2lc00394een
dc.identifier.doi10.1039/d2lc00394e
dc.identifier.issn1473-0197
dc.identifier.urihttps://open.icm.edu.pl/handle/123456789/21650
dc.language.isoen
dc.publisherRoyal Society of Chemistryen
dc.rightsUznanie autorstwa 4.0 Międzynarodowe*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectmicrofluidicsen
dc.subjectantibiotic susceptibilityen
dc.titleMicrofluidics for antibiotic susceptibility testingen
dc.typearticleen
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