The impact of type II diabetes on the risk of atrial fibrillation – literature review

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Authors
Mazurek, Aleksandra ORCID logo 0000-0003-0620-2503
Machaj, Damian ORCID logo 0009-0007-8299-0990
Machaj, Dominik ORCID logo 0000-0001-9402-8693
Date
2025-12-11
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Publisher
Medical University of Gdańsk
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Creative Commons License
Attribution-ShareAlike 4.0 International
Abstract
Atrial fibrillation (AF) is the most common type of supraventricular arrhythmia, affecting an estimated 40 million people worldwide. Type 2 diabetes mellitus (T2DM) is a common disease among cardiac patients, and hyperglycemia has a significant impact on cardiovascular function. Oxidative stress causes microvascular damage, while the increased production of vascular endothelial growth factor (VEGF) affects the endothelium, leading to its dysfunction. These factors, along with diabetic cardiomyopathy, contribute to hyperglycemia-induced changes in the vessels, and myocardium, thereby predisposing patients to the development of AF. The aim of this review was to discuss and analyse the factors linking AF with T2DM.
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Keywords
atrial fibrillation  diabetes mellitus type 2  hyperglycemia
Citation
Mazurek A, Machaj D, Machaj D. The impact of type II diabetes on the risk of atrial fibrillation – literature review. Eur J Transl Clin Med. 2025;8(2):86-90. https://doi.org/10.31373/ejtcm/213788
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https://open.icm.edu.pl/handle/123456789/26423
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