Novel cardiovascular risk factors in young women with classical risk profiles
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EJTCM_2026_9_1_Hulliel.pdf (539.22 KB)
Authors
0000-0002-2581-7012 Date
2026-03-17
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Gdański Uniwersytet Medyczny
Abstract
Introduction: Urbanization plays a growing role in the development of atherosclerotic cardiovascular disease (ASCVD) across the Middle East, particularly among younger adults. Yet, we still know very little about how the health profiles of young women differ between urban and rural settings. In this study, we aim to bridge that gap by examining the demographic characteristics and the prevalence of both classical and novel ASCVD risk factors in young Middle Eastern women. Methods: We analyzed the demographic, social, and clinical profiles of women aged 18-50 years, including 19 classical and novel ASCVD risk factors. We included participants living in either urban or rural areas, recruited from 11 centers across Jordan and 1 in the Gaza Strip between August 2020 and October 2023. Results: Of the 627 women studied (mean age 44.2 ± 5.1 years), 74% lived in urban areas and 26% in rural areas. ASCVD was present in 32.0% of urban and 37.3% of rural participants. Rural women had higher rates of physical inactivity, obesity, and elevated BMI, while smoking was more common among urban women. Among novel risk factors, premature menopause and depression were more frequent in urban women, whereas hypertensive disorders of pregnancy were more common in rural women. Conclusion: Urban young women demonstrated a worse clinical profile, with higher prevalence of several key ASCVD risk factors.
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Ibdah A, Alkhawaldeh M, Ibdah R, Hulliel A, Rawashdeh S, Al-Akhras A, Abedal-Kareem K, Wahbeh L, Khader S, Baker M, Eid S, Mansi J A, Khraisat R, Alsahan M H, Al-Rhayyel Y, Alawajneh M M, Dayah S A, Mahmoud S, Hammoudeh A. Novel cardiovascular risk factors in young women with classical risk profiles. Eur J Transl Clin Med. 2026;9(1):36-45