Synthetic Organic Chemistry of α-Imino Ketones: A Graphical Review

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dc.contributor.authorPareek, Abhishek
dc.contributor.authorYaragorla, Srinivasarao
dc.contributor.organizationInstitute of Organic Chemistry, Polish Academy of Sciences
dc.contributor.organizationSchool of Chemistry, University of Hyderabad, P.O. Central University, India
dc.date.accessioned2025-08-28T11:28:12Z
dc.date.available2025-08-28T11:28:12Z
dc.date.issued2024
dc.description.abstractα-Imino ketones are traditionally synthesized through condensing simple and readily available α-keto aldehydes or 1,2-diketones with primary or secondary amines. They are structurally similar to many naturally occurring biological substances due to the presence of the imino group (–N=C–). Chemically, C-acylimines exhibit ambiphilic reactivity, making their synthetic chemistry particularly attractive and viable for the creation of various aza-cyclic and heterocyclic compounds, including their asymmetric counterparts. Consequently, numerous synthetic strategies have been developed starting from these building blocks. Herein, we provide a graphical review of state-of-the-art synthetic efforts over the past 20 years, focusing on the use of α-imino ketones (both cyclic and acyclic) for the synthesis of small molecules and complex systems.en
dc.identifier.citationSynOpen 2024; 08(04): 265-272. DOI: 10.1055/s-0040-1720150
dc.identifier.doi10.1055/s-0040-1720150
dc.identifier.issn2509-9396
dc.identifier.urihttps://open.icm.edu.pl/handle/123456789/26086
dc.language.isoen
dc.publisherStuttgart: Thieme
dc.rightsUznanie autorstwa 4.0 Międzynarodoween
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceSynOpen
dc.subjectα-imino ketonesen
dc.subjectC-acyliminesen
dc.subjectambiphilic reactivityen
dc.subjectcycloadditionsen
dc.subjectannulationsen
dc.subjectasymmetric synthesisen
dc.titleSynthetic Organic Chemistry of α-Imino Ketones: A Graphical Reviewen
dc.typearticle
dc.type.versionpublishedVersion
person.identifier.orcidYaragorla, Srinivasarao [0000-0001-6152-5861]
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