Bacteriophage-based biosensors: detection of bacteria and beyond

Paczesny, Jan; Wdowiak, Mateusz; Ochirbat, Enkhlin

Bacteriophage-based biosensors: detection of bacteria and beyond

Abstract

Pathogenic infections cause tremendous health threats and socioeconomic burdens worldwide. Conventional methods for bacteria detection are laborious, time-consuming, expensive, require particular devices, and highly qualified specialists. Sensitive, selective, inexpensive, quick, and user-friendly biosensors are in urgent demand to prevent and detect bacterial infections in many fields, e.g., healthcare, food industry, or terrorism prevention. Among biorecognition elements utilized in biosensors, bacteriophages are highly promising due to their numerous advantages, such as host specificity, cheap and simple production, resistance to external factors, and ease of immobilization. Here we reviewed currently used methods for bacteria detection, pointing their advantages and disadvantages. We paid particular attention to bacteriophage-based methods, including phage-based sensors and phage display method.

Description

Plik zdeponowany po upływie okresu embargo (24 miesiące).

Keywords

bacteria bacteriophage biosensor detection applications

Citation

Paczesny, J., Wdowiak, M., Ochirbat, E. (2022). Bacteriophage-Based Biosensors: Detection of Bacteria and Beyond. In: Hameed, S., Rehman, S. (eds) Nanotechnology for Infectious Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-16-9190-4_20