Challenges in orthodontic treatment of patients after childhood cancer disease – a literature review

Abstract
Nowadays, cancer in children is increasingly common. Thanks to effective treatment, survival rates are continually rising. However, the applied chemotherapy, radiotherapy, or combined treatment leaves a number of side effects. There are disturbances in growth, including within the bones of the craniofacial complex, as well as developmental anomalies in dentition. Among these, the most frequently observed are defects in the structure of tooth roots, tooth agenesis and microdontia. These disorders cause aesthetic and occlusal problems, therefore there is a need to modify the orthodontic treatment plan for patients after cancer therapy. The higher risk of caries in these patients (due to xerostomia and enamel hypoplasia) complicates or even makes it impossible to achieve the intended results of orthodontic treatment. We analysed the available literature in Scopus, PubMed and Google Scholar databases from the years 2010-2022 to understand the challenges orthodontists face when treating patients who experienced cancer in childhood.
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Maciejewska J, Racka-Pilszak B. Challenges in orthodontic treatment of patients after childhood cancer disease – a literature review. Eur J Transl Clin Med. 2025;8(2):43-57. https://doi.org/10.31373/ejtcm/208477
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